No because the chemicals are intended to aid the fracking process. They are meant to reduce pressure in the well, aid in lubrication of the well and prevent corrosion of the well casing. Without the chemicals, the well casings would degrade causing cracks and fissures. Also, pressure inside the well would increase.
To frack without the fluid might alleviate concerns about the chemicals coming into contact with water and soil, but it would almost guarantee methane and other gasses causing ruptures in the well containment and contaminating water and soil.